(R)-4-(1-Aminoethyl)benzoic acid is a chiral organic compound with the chemical formula C10H13NO2.
Nature:
(R)-4-(1-Aminoethyl)benzoic acid is a white crystalline solid with a melting point of about 181-183°C. It is slightly soluble in water and soluble in some organic solvents such as ethanol and dimethylformamide. It is a light-sensitive compound that may react chemically under light conditions.
Use:
(R)-4-(1-Aminoethyl)benzoic acid has some applications in the field of medicine. It can be used as an important intermediate for the synthesis of other drug molecules. It can also be used in the synthesis of chiral ligands and chiral catalysts.
Method:
The preparation method of (R)-4-(1-Aminoethyl)benzoic acid is relatively complicated. A commonly used synthetic route is esterification of p-Hydroxybenzoic acid, followed by amination under alkaline conditions, and finally the target product is obtained by suitable chiral resolution means.
Safety Information:
Specific toxicity and safety information for (R)-4-(1-Aminoethyl)benzoic acid has not been clearly reported, but as a chemical, it is important to follow basic laboratory safety practices, avoid contact with skin and eyes, away from fire. Wear appropriate personal protective equipment to ensure good ventilation when using or handling the compound. In case of intentional contact or ingestion, seek medical advice immediately and carry the compound's safety data sheet.